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Nucleic Acid Hybridization

Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)

Year introduced: 1972(1971)

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Tree Number(s): E05.393.661, G02.111.611

MeSH Unique ID: D009693

Entry Terms:

  • Acid Hybridization, Nucleic
  • Acid Hybridizations, Nucleic
  • Hybridization, Nucleic Acid
  • Hybridizations, Nucleic Acid
  • Nucleic Acid Hybridizations
  • Genomic Hybridization
  • Genomic Hybridizations
  • Hybridization, Genomic
  • Hybridizations, Genomic

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