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A biologically active tridecapeptide isolated from the hypothalamus. It has been shown to induce hypotension in the rat, to stimulate contraction of guinea pig ileum and rat uterus, and to cause relaxation of rat duodenum. There is also evidence that it acts as both a peripheral and a central nervous system neurotransmitter.

Year introduced: 1978

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Tree Number(s): D12.644.400.550, D12.776.631.650.550

MeSH Unique ID: D009496

Registry Number: 39379-15-2

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