NFATC Transcription Factors

A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.

Year introduced: 2006(1993)

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D12.776.930.608

MeSH Unique ID: D050778

Entry Terms:

• Transcription Factors, NFATC
• NFATC Proteins
• Nuclear Factor of Activated T-Cells, Cytoplasmic
• Nuclear Factor of Activated T Cells, Cytoplasmic
• NFAT Proteins
• Nuclear Factors of Activated T-Cells
• Nuclear Factors of Activated T Cells
• Transcription Factor NF-AT
• NF-AT, Transcription Factor
• Transcription Factor NF AT
• NF-AT Proteins
• NF AT Proteins
• NFAT Transcription Factor 3
• Nuclear Factor of Activated T-Cells, Cytoplasmic 4 Protein
• Nuclear Factor of Activated T Cells, Cytoplasmic 4 Protein
• NF-AT3 Protein
• NF AT3 Protein
• NFAT3 Protein
• NFATC4 Protein
• NFATC4 Transcription Factor
• Transcription Factor, NFATC4
• NFAT Transcription Factor 4
• NFATC3 Transcription Factor
• Factor, NFATC3 Transcription
• Transcription Factor, NFATC3
• NFATx Protein
• NFATC3 Protein
• NF-AT4 Protein
• NF AT4 Protein
• NFAT4 Protein
• Nuclear Factor of Activated T-Cells, Cytoplasmic 3 Protein
• Nuclear Factor of Activated T Cells, Cytoplasmic 3 Protein
• NFAT Transcription Factor 1
• Nuclear Factor of Activated T-Cells, Cytoplasmic 2 Protein
• Nuclear Factor of Activated T Cells, Cytoplasmic 2 Protein
• NFAT-1 Protein
• NFAT 1 Protein
• NFAT1 Protein
• NFATC2 Protein
• NFATC2 Transcription Factor
• Factor, NFATC2 Transcription
• Transcription Factor, NFATC2
• NFAT Transcription Factor 2
• NF-ATc1 Protein
• NF ATc1 Protein
• NFAT-2 Protein
• NFAT 2 Protein
• NFAT2 Protein
• NFATC1 Protein
• NFATC1 Transcription Factor
• Factor, NFATC1 Transcription
• Transcription Factor, NFATC1
• Nuclear Factor of Activated T-Cells, Cytoplasmic 1 Protein
• Nuclear Factor of Activated T Cells, Cytoplasmic 1 Protein
• NFAT Transcription Factor 5
• Nuclear Factor of Activated T-Cells 5 Protein
• Nuclear Factor of Activated T Cells 5 Protein
• OREBP Protein
• Osmotic Response Element Binding Protein
• TonEBP Protein
• Tonicity-Responsive Enhancer-Binding Protein
• Tonicity Responsive Enhancer Binding Protein
• NFAT5 Protein
• NFATz Protein
• NFATL1 Protein

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Transcription Factors
NFATC Transcription Factors