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Macrophage Colony-Stimulating Factor

A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).

Year introduced: 1991

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Tree Number(s): D12.644.276.374.410.240.500, D12.776.395.240.500, D12.776.467.374.410.240.500, D23.529.374.410.240.500

MeSH Unique ID: D016173

Registry Number: 81627-83-0

Entry Terms:

  • M-CSF
  • CSF-1
  • CSF-M
  • Colony-Stimulating Factor 1
  • Colony Stimulating Factor 1
  • Colony-Stimulating Factor, Macrophage
  • Colony Stimulating Factor, Macrophage

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