Macrophage Activation

The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.

Year introduced: 1982

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Tree Number(s): G12.287.500

MeSH Unique ID: D008262

Entry Terms:

• Activation, Macrophage
• Activations, Macrophage
• Macrophage Activations

Previous Indexing:

• Macrophages (1966-1981)

All MeSH Categories
Phenomena and Processes Category
Immune System Phenomena
Cytotoxicity, Immunologic
Macrophage Activation