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Lymphocyte Specific Protein Tyrosine Kinase p56(lck)

This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.

Year introduced: 1998

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Subheadings:

Tree Number(s): D08.811.913.696.620.682.725.800.315, D12.776.624.664.700.128

MeSH Unique ID: D019860

Registry Number: EC 2.7.10.2

Entry Terms:

  • p56 lck
  • Proto-Oncogene Protein c-lck
  • Protein c-lck, Proto-Oncogene
  • Proto Oncogene Protein c lck
  • c-lck, Proto-Oncogene Protein
  • Proto-Oncogene Protein lck
  • Protein lck, Proto-Oncogene
  • Proto Oncogene Protein lck
  • lck, Proto-Oncogene Protein
  • lck Kinase
  • Kinase, lck
  • Protein Tyrosine Kinase p56(lck)

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