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Lymphocyte Activation

Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.

Year introduced: 2003 (1969)

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Tree Number(s): E01.370.225.812.482, E05.200.812.482, E05.478.594.530, G12.450.050.400.545, G12.565

MeSH Unique ID: D008213

Entry Terms:

  • Activation, Lymphocyte
  • Blast Transformation
  • Blastogenesis
  • Lymphocyte Stimulation
  • Stimulation, Lymphocyte
  • Lymphocyte Transformation
  • Transformation, Lymphoblast
  • Lymphoblast Transformation
  • Transformation, Blast
  • Transformation, Lymphocyte

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