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Loss of Heterozygosity

The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted.

Year introduced: 1998

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Subheadings:

Tree Number(s): G05.365.590.029.530

MeSH Unique ID: D019656

Entry Terms:

  • Heterozygosity Loss
  • Allelic Loss
  • Allelic Losses
  • Heterozygosity, Loss of

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