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Lipoproteins, HDL

A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.

Year introduced: 1974(1972)

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Tree Number(s): D10.532.432, D12.776.521.479

MeSH Unique ID: D008075

Entry Terms:

  • HDL Lipoproteins
  • Heavy Lipoproteins
  • Lipoproteins, Heavy
  • High-Density Lipoproteins
  • High Density Lipoproteins
  • Lipoproteins, High-Density
  • alpha-Lipoproteins
  • alpha Lipoproteins
  • alpha-1 Lipoprotein

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