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Leucine Zippers

DNA-binding motifs formed from two alpha-helixes which intertwine for about eight turns into a coiled coil and then bifurcate to form Y shaped structures. Leucines occurring in heptad repeats end up on the same sides of the helixes and are adjacent to each other in the stem of the Y (the "zipper" region). The DNA-binding residues are located in the bifurcated region of the Y.

Year introduced: 1991

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Subheadings:

Tree Number(s): G02.111.570.820.709.275.500.520

MeSH Unique ID: D016350

Entry Terms:

  • Leucine Zipper
  • Zipper, Leucine
  • Zippers, Leucine

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