Kainic Acid

(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.

Year introduced: 1986(1978)

Date introduced: April 22, 1977

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Tree Number(s): D03.383.773.400

MeSH Unique ID: D007608

Registry Number: SIV03811UC

Entry Terms:

• Acid, Kainic
• Digenic Acid
• Acid, Digenic
• Kainate

Previous Indexing:

• Pyrrolidines (1966-1977)

See Also:

• Receptors, Kainic Acid

Pharmacologic Action:

• Antinematodal Agents
• Excitatory Amino Acid Agonists

All MeSH Categories
Chemicals and Drugs Category
Heterocyclic Compounds
Heterocyclic Compounds, 1-Ring
Pyrrolidines
Kainic Acid