Interleukin-12
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.
Year introduced: 1995 (1991)
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Tree Number(s): D12.644.276.374.465.512, D12.776.467.374.465.512, D23.529.374.465.512
MeSH Unique ID: D018664
Registry Number: 187348-17-0
Entry Terms:
- Interleukin 12
- Natural Killer Cell Stimulatory Factor
- IL12
- IL 12
- IL-12 p70
- Interleukin-12 p70
- Interleukin 12 p70
- IL-12
- Cytotoxic Lymphocyte Maturation Factor
- Edodekin Alfa
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