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Insulin-Like Growth Factor I

A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.

Year introduced: 1991(1986)

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Subheadings:

Tree Number(s): D12.644.276.937.400, D12.776.124.862.400, D12.776.467.937.400, D23.529.937.400

MeSH Unique ID: D007334

Registry Number: 67763-96-6

Entry Terms:

  • Insulin-Like Somatomedin Peptide I
  • Insulin Like Somatomedin Peptide I
  • Somatomedin C
  • IGF-I-SmC
  • IGF-1
  • IGF-I
  • Insulin Like Growth Factor I

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