Inositol 1,4,5-Trisphosphate

Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.

Year introduced: 1990

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D02.033.800.519.400.350, D09.853.519.400.350, D09.894.480.350

MeSH Unique ID: D015544

Registry Number: 85166-31-0

Entry Terms:

• 1,4,5-IP3
• Myo-Inositol 1,4,5-Trisphosphate
• Myoinositol 1,4,5-Triphosphate
• 1,4,5-InsP3
• Inositol 1,4,5-Triphosphate

Previous Indexing:

• Inositol Phosphates (1978-1989)
• Sugar Phosphates (1974-1977)

All MeSH Categories
Chemicals and Drugs Category
Organic Chemicals
Alcohols
Sugar Alcohols
Inositol
Inositol Phosphates
Inositol 1,4,5-Trisphosphate

All MeSH Categories
Chemicals and Drugs Category
Carbohydrates
Sugar Alcohols
Inositol
Inositol Phosphates
Inositol 1,4,5-Trisphosphate

All MeSH Categories
Chemicals and Drugs Category
Carbohydrates
Sugar Phosphates
Inositol Phosphates
Inositol 1,4,5-Trisphosphate