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Inositol 1,4,5-Trisphosphate

Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.

Year introduced: 1990

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Tree Number(s): D02.033.800.519.400.350, D09.853.519.400.350, D09.894.480.350

MeSH Unique ID: D015544

Registry Number: 85166-31-0

Entry Terms:

  • Inositol 1,4,5-Triphosphate
  • Myoinositol 1,4,5-Triphosphate
  • 1,4,5-InsP3
  • 1,4,5-IP3
  • Myo-Inositol 1,4,5-Trisphosphate

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