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I-kappa B Proteins

A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.

Year introduced: 2006(2000)

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Tree Number(s): D12.644.360.365, D12.776.260.420, D12.776.476.381, D12.776.930.326

MeSH Unique ID: D020672

Entry Terms:

  • I kappa B Proteins
  • I kappa B
  • IkB DNA-Binding Proteins
  • IkB DNA Binding Proteins
  • I-kappa B

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