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Host Cell Factor C1

A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION.

Year introduced: 2006(1995)

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Subheadings:

Tree Number(s): D12.776.660.478, D12.776.930.325

MeSH Unique ID: D051863

Entry Terms:

  • Cell Proliferation Factor HCF
  • HCFC1 Protein
  • C1 Host Cell Factor

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