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Histamine Release

The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's Fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects.

Year introduced: 1996

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Tree Number(s): G12.350

MeSH Unique ID: D006636

Entry Terms:

  • Histamine Releases
  • Histamine Liberation
  • Histamine Liberations

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