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HLA-C Antigens

Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).

Year introduced: 1989

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Tree Number(s): D12.776.395.550.489.600, D12.776.543.550.439.600, D23.050.301.500.100.600, D23.050.301.500.450.390, D23.050.705.552.100.600, D23.050.705.552.450.390

MeSH Unique ID: D015236

Entry Terms:

  • HLA C Antigens
  • HLA-C
  • Antigens, HLA-C
  • Antigens, HLA C

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