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HIV Envelope Protein gp120

External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.

Year introduced: 1990

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Tree Number(s): D12.776.964.775.325.164.249, D12.776.964.775.562.500.500, D12.776.964.970.880.325.164.249, D23.050.327.520.350

MeSH Unique ID: D015699

Entry Terms:

  • Envelope Glycoprotein gp120, HIV
  • gp120 Envelope Glycoprotein, HIV
  • HIV Envelope Glycoprotein gp120
  • HTLV-III gp120
  • HTLV III gp120
  • gp120, HTLV-III
  • env Protein gp120, HIV
  • gp120(HIV)

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