Genes, Lethal

Genes whose loss of function or gain of function MUTATION leads to the death of the carrier prior to maturity. They may be essential genes (GENES, ESSENTIAL) required for viability, or genes which cause a block of function of an essential gene at a time when the essential gene function is required for viability.

Year introduced: 1968

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Tree Number(s): G05.360.340.024.340.350

MeSH Unique ID: D005804

Entry Terms:

• Gene, Lethal
• Lethal Gene
• Lethal Genes
• Alleles, Lethal
• Allele, Lethal
• Lethal Allele
• Lethal Alleles

Previous Indexing:

• Genes (1966-1967)

See Also:

• Synthetic Lethal Mutations

All MeSH Categories
Phenomena and Processes Category
Genetic Phenomena
Genetic Structures
Genome
Genome Components
Genes
Genes, Lethal