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Gastrinoma

A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1).

Year introduced: 1989

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Tree Number(s): C04.557.470.200.025.290.500, C04.588.274.761.500.124, C04.588.322.475.500.124, C06.301.761.500.124, C06.689.667.500.124, C19.344.421.500.124

MeSH Unique ID: D015408

Entry Terms:

  • Gastrinomas
  • Islet Cell Tumor, Ulcerogenic
  • Ulcerogenic Islet Cell Tumor
  • Gastrin-Producing Tumor
  • Gastrin Producing Tumor
  • Gastrin-Producing Tumors
  • Tumor, Gastrin-Producing
  • Tumors, Gastrin-Producing

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