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Frizzled Receptors

A family of seven-pass transmembrane cell-surface proteins that combines with LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 or LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 to form receptors for WNT PROTEINS. Frizzled receptors often couple with HETEROTRIMERIC G PROTEINS and regulate the WNT SIGNALING PATHWAY.

Year introduced: 2006(1998)

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Subheadings:

Tree Number(s): D12.776.543.750.695.017, D12.776.543.750.850.500

MeSH Unique ID: D051157

Entry Terms:

  • Frizzled Proteins
  • Frizzled Receptor
  • Receptor, Frizzled
  • Receptors, Frizzled

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