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Fibrinolysin

A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins.

Year introduced: 2010, 1963-1992

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Subheadings:

Tree Number(s): D08.811.277.656.300.760.330, D08.811.277.656.959.350.330

MeSH Unique ID: D005341

Registry Number: EC 3.4.21.7

Entry Terms:

  • Plasmin
  • Protease F
  • Glu-Plasmin
  • Glu Plasmin
  • Fibrogammin
  • Thrombolysin

Pharmacologic Action:

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