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A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)

Year introduced: 2004(1997)

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Tree Number(s): D12.644.276.400.225, D12.776.467.400.225, D23.529.400.225

MeSH Unique ID: D019332

Entry Terms:

  • Endothelin 1
  • Endothelin Type 1
  • Proendothelin (1-38)
  • Big Endothelin
  • Big Endothelin-1
  • Big Endothelin 1
  • Endothelin-1, Big
  • Endothelin, Big
  • Preproendothelin-1
  • Preproendothelin 1
  • Preproendothelin
  • Proendothelin-1 Precursor
  • Precursor, Proendothelin-1
  • Proendothelin 1 Precursor

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