Format

Send to:

Choose Destination

Dystrophin

A muscle protein localized in surface membranes which is the product of the Duchenne/Becker muscular dystrophy gene. Individuals with Duchenne muscular dystrophy usually lack dystrophin completely while those with Becker muscular dystrophy have dystrophin of an altered size. It shares features with other cytoskeletal proteins such as SPECTRIN and alpha-actinin but the precise function of dystrophin is not clear. One possible role might be to preserve the integrity and alignment of the plasma membrane to the myofibrils during muscle contraction and relaxation. MW 400 kDa.

Year introduced: 1991

PubMed search builder options

Subheadings:

Tree Number(s): D12.776.210.500.250, D12.776.220.250, D12.776.543.250

MeSH Unique ID: D016189

Previous Indexing:

See Also:

Supplemental Content

Loading ...
Support Center