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Dizocilpine Maleate

A potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) used mainly as a research tool. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role. Its use has been primarily limited to animal and tissue experiments because of its psychotropic effects.

Year introduced: 1991

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Subheadings:

Tree Number(s): D02.455.426.559.847.181.384.380, D04.615.181.384.380

MeSH Unique ID: D016291

Registry Number: 6LR8C1B66Q

Entry Terms:

  • Dizocilpine
  • MK-801
  • MK 801
  • MK801

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Pharmacologic Action:

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