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A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.

Year introduced: 1965(1963)

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Tree Number(s): D03.633.300.240.281

MeSH Unique ID: D003891

Registry Number: TG537D343B

Entry Terms:

  • Desmethylimipramine
  • Demethylimipramine
  • Desipramine Hydrochloride
  • Hydrochloride, Desipramine
  • Norpramin
  • Ratio-Desipramine
  • Ratio Desipramine
  • Nu-Desipramine
  • Nu Desipramine
  • Pertofrane
  • Pertrofran
  • Pertofran
  • Petylyl
  • PMS-Desipramine
  • PMS Desipramine
  • Apo-Desipramine
  • Apo Desipramine
  • Novo-Desipramine
  • Novo Desipramine

Pharmacologic Action:

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