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DNA Polymerase I

A DNA-dependent DNA polymerase characterized in prokaryotes and may be present in higher organisms. It has both 3'-5' and 5'-3' exonuclease activity, but cannot use native double-stranded DNA as template-primer. It is not inhibited by sulfhydryl reagents and is active in both DNA synthesis and repair. EC 2.7.7.7.

Year introduced: 1984(1977)

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Tree Number(s): D08.811.913.696.445.308.300.225

MeSH Unique ID: D004256

Registry Number: EC 2.7.7.-

Entry Terms:

  • Polymerase I, DNA
  • Klenow Fragment
  • DNA-Dependent DNA Polymerase I
  • DNA Dependent DNA Polymerase I
  • DNA Pol I
  • DNA Polymerase alpha
  • Polymerase alpha, DNA

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