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Cytochrome P-450 CYP2D6

A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population.

Year introduced: 1997

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Tree Number(s): D08.244.453.005.600, D08.244.453.491.372, D08.811.682.690.708.170.010.600, D08.811.682.690.708.170.450.368, D12.776.422.220.453.010.600, D12.776.422.220.453.491.368

MeSH Unique ID: D019389

Registry Number: EC

Entry Terms:

  • CYP2D6, Cytochrome P-450
  • Cytochrome P 450 CYP2D6
  • P-450 CYP2D6, Cytochrome
  • Sparteine Monooxygenase
  • Monooxygenase, Sparteine
  • Cytochrome P450 2D6
  • P450 2D6, Cytochrome
  • Debrisoquine 4-Monooxygenase
  • 4-Monooxygenase, Debrisoquine
  • Debrisoquine 4 Monooxygenase
  • Imipramine 2-Hydroxylase
  • 2-Hydroxylase, Imipramine
  • Imipramine 2 Hydroxylase
  • CYP2D6
  • CYP 2D6
  • Debrisoquine 4-Hydroxylase
  • 4-Hydroxylase, Debrisoquine
  • Debrisoquine 4 Hydroxylase
  • Debrisoquine Hydroxylase
  • Hydroxylase, Debrisoquine

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