Cyclin-Dependent Kinase 2
A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.
Year introduced: 2006(1991)
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Subheadings:
Tree Number(s): D08.811.913.696.620.682.700.646.500.750, D12.776.167.200.323, D12.776.476.563.646.500.750
MeSH Unique ID: D051357
Registry Number: EC 2.7.11.22
Entry Terms:
- Cyclin Dependent Kinase 2
- p33cdk2 Kinase
- CDK2 Protein
- Cdc2-Related Protein Kinase
- Cdc2 Related Protein Kinase
- Cdk2 Protein Kinase