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Cortactin

A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).

Year introduced: 2006(1983)

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Tree Number(s): D05.750.078.730.281, D12.644.360.024.280, D12.776.157.057.014, D12.776.220.525.281, D12.776.476.024.311, D12.776.744.390

MeSH Unique ID: D051356

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