Core Binding Factor Alpha 2 Subunit

A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.

Year introduced: 2006(1993)

PubMed search builder options

Subheadings:

Restrict to MeSH Major Topic.

Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D12.776.930.155.200.200

MeSH Unique ID: D050676

Entry Terms:

• Acute Myeloid Leukemia 1 Protein
• Core-Binding Factor Alpha 2 Protein
• Core Binding Factor Alpha 2 Protein
• Pebp2a2 Protein
• Runt-Related Transcription Factor 1
• Runt Related Transcription Factor 1
• Runx1 Protein
• Acute Myeloid Leukemia 1A Protein
• AML1A Protein
• Acute Myeloid Leukemia 1B Protein
• AML1B Protein
• Acute Myeloid Leukemia 1D Protein
• AML1D Protein
• Acute Myeloid Leukemia 1C Protein
• AML1C Protein

Previous Indexing:

• DNA-Binding Proteins (1996-2005)
• Neoplasm Proteins (1993-1996)
• Proto-Oncogene Proteins (1996-2005)
• Transcription Factors (1996-2005)

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Transcription Factors
Core Binding Factors
Core Binding Factor alpha Subunits
Core Binding Factor Alpha 2 Subunit