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Complement C4b

The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).

Year introduced: 2006 (1990)

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Tree Number(s): D12.776.124.486.274.350.260

MeSH Unique ID: D015935

Registry Number: 80295-50-7

Entry Terms:

  • C4b, Complement
  • Complement 4b
  • Complement Component 4b
  • Component 4b, Complement
  • C4b Complement
  • Complement, C4b

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Pharmacologic Action:

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