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Complement C2

A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).

Year introduced: 2006 (1975)

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Subheadings:

Tree Number(s): D12.776.124.486.274.150

MeSH Unique ID: D003175

Entry Terms:

  • C2, Complement
  • Complement 2
  • Complement Component 2
  • Component 2, Complement
  • C2 Complement
  • Complement, C2

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