Coagulase
Enzymes that cause coagulation in plasma by forming a complex with human PROTHROMBIN. Coagulases are produced by certain STAPHYLOCOCCUS and YERSINIA PESTIS. Staphylococci produce two types of coagulase: Staphylocoagulase, a free coagulase that produces true clotting of plasma, and Staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen.
Year introduced: 1966(1964)
Date introduced: January 1, 1999
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Subheadings:
Tree Number(s): D08.811.277.656.300.174, D12.776.097.181
MeSH Unique ID: D003030
Entry Terms:
- Staphylococcal Clumping Factor
- Clumping Factor, Staphylococcal
- Factor, Staphylococcal Clumping
- Clumping Factor (Staphylococcal)
- Staphylocoagulase
- Staphylococcus aureus clone pSCa2 of Coagulase
- Staphylococcus aureus strain 213 of Coagulase
- Staphylococcus aureus strain 8325-4 of Coagulase
- Staphylococcus aureus strain 8325 4 of Coagulase
Pharmacologic Action: