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A group of acidic proteins that are major components of SECRETORY GRANULES in the endocrine and neuroendocrine cells. They play important roles in the aggregation, packaging, sorting, and processing of secretory protein prior to secretion. They are cleaved to release biologically active peptides. There are various types of granins, usually classified by their sources.

Year introduced: 1991(1973)

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Tree Number(s): D12.776.631.199, D12.776.811.185

MeSH Unique ID: D002864

Entry Terms:

  • Granins
  • Secretogranins

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