Caspase 9
A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
Year introduced: 2007(2005)
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Subheadings:
Tree Number(s): D08.811.277.656.262.500.126.550.900, D08.811.277.656.300.200.126.550.900, D12.644.360.024.131.155, D12.644.360.075.358.155, D12.644.360.075.405.550.900, D12.776.157.057.006.155, D12.776.476.024.139.155, D12.776.476.075.358.155, D12.776.476.075.405.550.900
MeSH Unique ID: D053453
Registry Number: EC 3.4.22.-
Entry Terms:
- ICE-Like Apoptotic Protease 6
- ICE Like Apoptotic Protease 6
- Apoptotic Protease Activating Factor 3
- ICE-LAP6 Protein
- ICE LAP6 Protein
- Caspase-9
- Procaspase-9
- Procaspase 9
- Pro-Caspase-9
- Pro Caspase 9