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Caspase 9

A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.

Year introduced: 2007(2005)

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Tree Number(s): D08.811.277.656.262.500.126.550.900, D08.811.277.656.300.200.126.550.900, D12.776., D12.776.476.024.139.155, D12.776.476.075.358.155, D12.776.476.075.405.550.900

MeSH Unique ID: D053453

Registry Number: EC 3.4.22.-

Entry Terms:

  • ICE-Like Apoptotic Protease 6
  • ICE Like Apoptotic Protease 6
  • Apoptotic Protease Activating Factor 3
  • ICE-LAP6 Protein
  • ICE LAP6 Protein
  • Caspase-9
  • Procaspase-9
  • Procaspase 9
  • Pro-Caspase-9
  • Pro Caspase 9

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