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Caspase 1

A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.

Year introduced: 1999

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Tree Number(s): D08.811.277.656.262.500.126.550.100, D08.811.277.656.300.200.126.550.100, D12.776.476.075.405.550.100

MeSH Unique ID: D020170

Registry Number: EC

Entry Terms:

  • Interleukin-1beta Converting Enzyme
  • Converting Enzyme, Interleukin-1beta
  • Interleukin 1beta Converting Enzyme
  • ICE Protease
  • IL1BC Enzyme
  • IL-1 beta Convertase
  • Convertase, IL-1 beta
  • IL 1 beta Convertase
  • beta Convertase, IL-1
  • CASP1 Caspase
  • Caspase, CASP1
  • Interleukin-1 Converting Enzyme
  • Converting Enzyme, Interleukin-1
  • Interleukin 1 Converting Enzyme
  • IL-1 beta-Converting Enzyme
  • IL 1 beta Converting Enzyme
  • beta-Converting Enzyme, IL-1
  • Procaspase-1
  • Procaspase 1
  • Pro-Caspase-1
  • Pro Caspase 1

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