Send to:

Choose Destination


Endogenous glycoproteins from which SIALIC ACID has been removed by the action of sialidases. They bind tightly to the ASIALOGLYCOPROTEIN RECEPTOR which is located on hepatocyte plasma membranes. After internalization by adsorptive ENDOCYTOSIS they are delivered to LYSOSOMES for degradation. Therefore receptor-mediated clearance of asialoglycoproteins is an important aspect of the turnover of plasma glycoproteins. They are elevated in serum of patients with HEPATIC CIRRHOSIS or HEPATITIS.

Year introduced: 1985

PubMed search builder options


Tree Number(s): D12.776.395.140

MeSH Unique ID: D001212

Entry Terms:

  • Desialylated Glycoproteins
  • Glycoproteins, Desialylated

Previous Indexing:

See Also:

Supplemental Content

Loading ...
Support Center