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Arachidonate 5-Lipoxygenase

An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes.

Year introduced: 1991(1987)

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Subheadings:

Tree Number(s): D08.811.682.690.416.583.500.055, D12.776.556.579.374.568.500.020

MeSH Unique ID: D001094

Registry Number: EC 1.13.11.34

Entry Terms:

  • 5-Lipoxygenase, Arachidonate
  • Arachidonate 5 Lipoxygenase
  • Arachidonic Acid 5-Lipoxygenase
  • 5-Lipoxygenase, Arachidonic Acid
  • Arachidonic Acid 5 Lipoxygenase
  • LTA4 Synthase
  • Synthase, LTA4
  • Leukotriene A4 Synthase
  • Synthase, Leukotriene A4
  • Leukotriene A4 Synthetase
  • Synthetase, Leukotriene A4
  • 5-Lipoxygenase
  • 5 Lipoxygenase
  • Leukotriene A Synthase
  • Synthase, Leukotriene A

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