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Apolipoproteins B

Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100 expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins. Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA.

Year introduced: 1985

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Subheadings:

Tree Number(s): D10.532.091.300, D12.776.070.400.300, D12.776.521.120.300

MeSH Unique ID: D001055

Entry Terms:

  • Apo-B
  • ApoB
  • Apo B
  • Apoproteins B
  • Apoprotein (B)

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