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Leukocyte Common Antigens

High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.

Year introduced: 2018 (1993)

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Tree Number(s): D08.811.277.352.650.775.400.100.500, D12.644.360.587.100.500, D12.776.476.592.100.500, D12.776.543.733.937.500

MeSH Unique ID: D017493

Registry Number: EC 3.1.3.48

Entry Terms:

  • Antigens, Leukocyte Common
  • CD45 Antigens
  • Antigens, CD45
  • Protein Tyrosine Phosphatase, Receptor Type, C
  • L-CA Antigens
  • Antigens, L-CA
  • L CA Antigens
  • Leukocyte Common Antigen
  • Antigen, Leukocyte Common
  • CD45 Antigen
  • Antigen, CD45
  • T200 Antigens
  • Antigens, T200
  • CD45RO Antigens
  • Antigens, CD45RO
  • CD45R0 Antigens
  • Antigens, CD45R0
  • CD45RB Antigens
  • Antigens, CD45RB
  • CD45RCAntigens
  • B220 Antigens
  • Antigens, B220
  • CD45R Antigens
  • Antigens, CD45R
  • B220 Antigen
  • Antigen, B220
  • CD45RA Antigens
  • Antigens, CD45RA
  • 2H4 Antigens
  • Antigens, 2H4

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