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An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver and secreted into blood circulation. Angiotensinogen is the inactive precursor of natural angiotensins. Upon successive enzyme cleavages, angiotensinogen yields angiotensin I, II, and III with amino acids numbered at 10, 8, and 7, respectively.

Year introduced: 1987(1975)

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Tree Number(s): D12.644.456.073.070, D12.644.861.020, D12.776.811.070, D12.776.872.020

MeSH Unique ID: D000808

Registry Number: 11002-13-4

Entry Terms:

  • Serpin A8
  • Renin-Substrate
  • Renin Substrate
  • Hypertensinogen
  • Proangiotensin
  • Renin Substrate Tetradecapeptide
  • Tetradecapeptide, Renin Substrate

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