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Amyloid

A fibrous protein complex that consists of proteins folded into a specific cross beta-pleated sheet structure. This fibrillar structure has been found as an alternative folding pattern for a variety of functional proteins. Deposits of amyloid in the form of AMYLOID PLAQUES are associated with a variety of degenerative diseases. The amyloid structure has also been found in a number of functional proteins that are unrelated to disease.

Year introduced: 1968

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Subheadings:

Tree Number(s): D05.500.049, D12.776.049

MeSH Unique ID: D000682

Entry Terms:

  • Amyloid Substance
  • Substance, Amyloid
  • Amyloid Fibrils
  • Fibrils, Amyloid

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