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1-Alkyl-2-acetylglycerophosphocholine Esterase

A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA.

Year introduced: 2004(1983)

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Tree Number(s): D08.811.277.352.100.680.750.937.249

MeSH Unique ID: D043203

Registry Number: EC

Entry Terms:

  • 1 Alkyl 2 acetylglycerophosphocholine Esterase
  • Esterase, 1-Alkyl-2-acetylglycerophosphocholine
  • PAF Acetylhydrolase II
  • Acetylhydrolase II, PAF
  • Platelet-Activating Factor Hydrolase
  • Factor Hydrolase, Platelet-Activating
  • Hydrolase, Platelet-Activating Factor
  • Platelet Activating Factor Hydrolase
  • PAF 2-Acylhydrolase
  • PAF 2 Acylhydrolase
  • Lipoprotein-Associated Phospholipase A2
  • Lipoprotein Associated Phospholipase A2
  • Phospholipase A2, Lipoprotein-Associated
  • Lp-PLA(2)
  • Lp-PLA2
  • Lp PLA2
  • PAF 2-Acetylhydrolase
  • 2-Acetylhydrolase, PAF
  • PAF 2 Acetylhydrolase
  • PAF Acetylhydrolase
  • Acetylhydrolase, PAF
  • Lipoprotein-Associated Phospholipase A(2)
  • Platelet-activating Factor Acetylhydrolase IB
  • Platelet activating Factor Acetylhydrolase IB

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