rho-Associated Kinases
A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.
Year introduced: 2008
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Subheadings:
Tree Number(s): D08.811.913.696.620.682.700.814, D12.776.476.563.814
MeSH Unique ID: D054460
Registry Number: EC 2.7.11.1
Entry Terms:
- rho Associated Kinases
- rho-Kinase
- rho Kinase
- rho-Associated Kinase
- rho Associated Kinase
- ROK Kinase
- rho-Associated Coiled-Coil Kinase
- Coiled-Coil Kinase, rho-Associated
- rho Associated Coiled Coil Kinase
- ROCK Protein Kinases
- Protein Kinases, ROCK
- rho-Associated Kinase 1
- rho Associated Kinase 1
- rho-Associated Coiled-Coil Containing Protein Kinase 1
- rho Associated Coiled Coil Containing Protein Kinase 1
- ROCK-I Protein Kinase
- ROCK I Protein Kinase
- rho-Associated Kinase beta
- rho Associated Kinase beta
- rho-Associated Protein Kinase beta
- rho Associated Protein Kinase beta
- p160ROCK
- rho-Associated Kinase 2
- rho Associated Kinase 2
- p160 rhoA-Binding Kinase ROKalpha
- p160 rhoA Binding Kinase ROKalpha
- rho-Associated Kinase alpha
- rho Associated Kinase alpha
- rho-Associated Protein Kinase alpha
- rho Associated Protein Kinase alpha
- rho-Associated Coiled-Coil Containing Protein Kinase 2
- rho Associated Coiled Coil Containing Protein Kinase 2
- ROCK-II Protein Kinase
- ROCK II Protein Kinase