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Oxytocin
A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION.
Year introduced: ALPHA-HYPOPHAMINE was see OXYTOCIN 1977-1993
Receptors, Oxytocin
Cell surface proteins that bind oxytocin with high affinity and trigger intracellular changes which influence the behavior of cells. Oxytocin receptors in the uterus and the mammary glands mediate the hormone's stimulation of contraction and milk ejection. The presence of oxytocin and oxytocin receptors in neurons of the brain probably reflects an additional role as a neurotransmitter.
Year introduced: 1994
oxytocin, Gly-Lys-Arg- [Supplementary Concept]
Date introduced: September 24, 1985
oxytocin, 1-penicillamyl-O-MeTyr(2)- [Supplementary Concept]
RN given refers to (D-Val-L-Tyr)-isomer
Date introduced: December 5, 1984
oxytocin,1-(beta-mercapto-(beta, beta-cyclopentamethylene)propionic acid)-Tyr(OMe)(2)-Orn(8)- [Supplementary Concept]
Date introduced: November 7, 1984
atosiban [Supplementary Concept]
Date introduced: December 9, 1985
oxytocin, Thr(4)-Gly(7)- [Supplementary Concept]
RN given refers to parent cpd
Date introduced: June 19, 1985
oxytocin, (1-(2-hydroxy-3-mercaptopropionic acid))-Thr(4)-Gly(7)- [Supplementary Concept]
RN given refers to parent cpd(R)-isomer
Date introduced: August 2, 1984
oxytocin, (4-ethyl-Phe)(2)- [Supplementary Concept]
RN given refers to cpd without isomeric designation
Date introduced: August 22, 1983
oxytocin, 1,6-N-carbonyl-Lys- [Supplementary Concept]
Date introduced: January 1, 1978
oxytocin, 1,6-alpha-Asu- [Supplementary Concept]
Date introduced: January 1, 1976
oxytocin, N-acetyl-2-O-methyl-Tyr- [Supplementary Concept]
specific antagonist of oxytocin; an oxytocin receptor antagonist
Date introduced: January 1, 1974
mesotocin [Supplementary Concept]
Date introduced: January 1, 1972
ANTAG III [Supplementary Concept]
Date introduced: December 11, 1998
ANTAG II [Supplementary Concept]
ANTAG I [Supplementary Concept]
oxytocin, 1-d(CH2)5-(2-O-methyl)Tyr-Thr(4)-Orn(8)-Tyr-NH2(9)- [Supplementary Concept]
oxytocin receptor ligand
Date introduced: September 27, 1996
oxytocin, Hmp(1)-Phe(2)-Hgn(4)-Dab(Ala)(8)- [Supplementary Concept]
a vasopressin V1 receptor agonist; names for amino acids which are abbreviated Hmp & Hgn not known
Date introduced: July 8, 1993
oxytocin, Pmp(1)-Trp(2)-Cys(6)-Arg(8)- [Supplementary Concept]
an oxytocin antagonist
Date introduced: April 26, 1993
oxytocin, 3,2'-di-Me-Phe(2)- [Supplementary Concept]
Date introduced: December 26, 1992