Format
Items per page

Send to:

Choose Destination

Search results

Items: 15

1.

Codon, Nonsense

An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon.

Year introduced: 1995

2.

Nonsense Mediated mRNA Decay

An mRNA metabolic process that distinguishes a normal STOP CODON from a premature stop codon (NONSENSE CODON) and facilitates rapid degradation of aberrant mRNAs containing premature stop codons.

Year introduced: 2012

3.

Genes, Suppressor

Genes that have a suppressor allele or suppressor mutation (SUPPRESSION, GENETIC) which cancels the effect of a previous mutation, enabling the wild-type phenotype to be maintained or partially restored. For example, amber suppressors cancel the effect of an AMBER NONSENSE MUTATION.

Year introduced: 1991

4.

UPF2 protein, human [Supplementary Concept]

RefSeq NM_015542

Date introduced: November 23, 2002

5.

UPF3B protein, mouse [Supplementary Concept]

Date introduced: January 21, 2014

6.

SMG7 protein, Arabidopsis [Supplementary Concept]

has an evolutionarily conserved role in nonsense-mediated RNA decay and required for exit from meiosis; has been sequenced

Date introduced: December 18, 2008

7.

SMG5 protein, human [Supplementary Concept]

RefSeq NM_015327

Date introduced: January 1, 2007

8.

SMG6 protein, human [Supplementary Concept]

RefSeq NM_017575

Date introduced: August 6, 2006

9.

SMG7 protein, human [Supplementary Concept]

acts as a molecular link between mRNA surveillance and mRNA decay, RefSeq NM_014837

Date introduced: December 30, 2004

10.

Rent1 protein, mouse [Supplementary Concept]

contains zinc fingers and NTPase domains; RefSeq NM_030680

Date introduced: August 6, 2004

11.

UPF3B protein, human [Supplementary Concept]

RefSeq NM_023010

Date introduced: September 25, 2001

12.

UPF3A protein, human [Supplementary Concept]

RefSeq NM_023011

Date introduced: September 25, 2001

13.

UPF1 protein, human [Supplementary Concept]

RefSeq NM_002911

Date introduced: November 18, 1996

14.

UPF1 protein, rat [Supplementary Concept]

RefSeq XM_003751566

Date introduced: October 3, 2017

15.

UPF 3A protein, mouse [Supplementary Concept]

RefSeq NM_025924

Date introduced: August 30, 2016

Format
Items per page

Send to:

Choose Destination

Supplemental Content

Loading ...
Support Center