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A quinazoline derivative that inhibits EPIDERMAL GROWTH FACTOR RECEPTOR and HER2 (RECEPTOR, ERBB-2) tyrosine kinases. It is used for the treatment of advanced or metastatic breast cancer, where tumors overexpress HER2.

Year introduced: 2019 (2004)

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Tree Number(s): D03.633.100.786.516

MeSH Unique ID: D000077341

Registry Number: 0VUA21238F

Entry Terms:

  • N-(3-chloro-4-(((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-methylsulfonyl)ethyl)amino)methyl) -2-furyl)-4-quinazolinamine
  • Tykerb
  • GW 282974X
  • GW282974X
  • GW-282974X
  • GW572016
  • GW-572016
  • GW 572016
  • Lapatinib Ditosylate

Pharmacologic Action:

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