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Uveal melanoma [Supplementary Concept]

A melanoma that originates from uveal MELANOCYTES and is the most common primary intraocular malignancy. Tumors consist of four cell types: epitheloid, intermediate, mixed, and spindle. Somatic mutations in BAP1, GNAQ, GNA11, EIF1AX, and SF3B1 genes have been identified. OMIM: 155720

Date introduced: August 25, 2010

MeSH Unique ID: C536494

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Entry Terms:

  • Melanoma, Uveal
  • Melanoma of the Uvea

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